Table 4.

Adjusted Hazards Ratios for Tooth Loss and Periodontal Disease Outcomes per Each Additional Positive MetS Component, from Tooth-Level, Time-Varying Proportional Hazards Regression Models.

	IDF Criteriaa		NCEP-ATP III Criteriab
Disease Outcome	Disease Event Only	Composite Eventc	Disease Event Only	Composite Eventc
Tooth lossd	1.14 (1.03 to 1.26)		1.18 (1.06 to 1.30)
Pocket depth ≥5 mme	1.14 (1.05 to 1.23)	1.13 (1.06 to 1.20)	1.11 (1.03 to 1.20)	1.12 (1.05 to 1.19)
Clinical attachment loss ≥5 mmf	1.05 (0.99 to 1.12)	1.08 (1.02 to 1.14)	1.05 (0.98 to 1.12)	1.08 (1.02 to 1.14)
Alveolar bone loss ≥40%g	1.11 (1.01 to 1.21)	1.15 (1.07 to 1.23)	1.12 (1.02 to 1.22)	1.18 (1.10 to 1.26)
Tooth mobility ≥0.5 mmh	1.17 (1.04 to 1.32)	1.28 (1.18 to 1.39)	1.16 (1.03 to 1.31)	1.31 (1.21 to 1.42)

Data are presented as adjusted hazard ratios (95% confidence intervals).

HDL, high-density lipoprotein; IDF, International Diabetes Federation; MetS, metabolic syndrome; NCEP-ATP III, National Cholesterol Education Program Adult Treatment Panel III.

^aIDF criteria include the presence of 3 or more conditions: hypertension, impaired glucose tolerance, low HDL, hypertriglyceridemia, or waist circumference ≥94 cm (men).

^bNCEP-ATP III criteria include the presence of 3 or more conditions: hypertension, impaired glucose tolerance, low HDL, hypertriglyceridemia, or waist circumference ≥102 cm (men).

^cComposite event defined as either the periodontal measure reached the threshold level or the tooth was lost.

^dAdjusted for baseline age and highest level of education completed (high school, some college, college), and time-dependent values of cigarette use (no/yes), cigar use (no/yes), plaque on tooth (none/interproximal only versus interproximal plus at least 1 other surface), and number of decayed/filled surfaces per tooth.

^eDisease event adjusted for baseline age, education, pocket depth score, and time-dependent values of cigarette use, cigar use, and plaque. Composite event additionally adjusted for number of decayed/filled surfaces per tooth.

^fDisease event adjusted for baseline age, education, clinical attachment loss score, and time-dependent values of cigarette use, cigar use, and plaque. Composite event additionally adjusted for number of decayed/filled surfaces per tooth.

^gDisease event adjusted for baseline age, education, alveolar bone loss score, and time-dependent values of cigarette use, cigar use, and plaque. Composite event additionally adjusted for number of decayed/filled surfaces per tooth.

^hDisease event adjusted for baseline age, education, mobility score, and time-dependent values of cigarette use, cigar use, and plaque. Composite event additionally adjusted for number of decayed/filled surfaces per tooth.