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Family pedigrees and surface electrocardiograms in patients without SCN5A mutation. (A) Pedigree of the Family #1 with R421P IRX3 mutation. An arrow indicates the proband. (B) Pedigree of the Family #2 with P485T IRX3 mutation. An arrow indicates the proband. (C) Surface electrocardiogram of the proband in the Family #1 with R421P IRX3 mutation. Electrocardiogram showed coved type ST elevation in V1 and V2 (black arrows), and saddle-back type ST elevation in V3 (grey arrow).
