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. 2016 Jun 21;6:28196. doi: 10.1038/srep28196

Figure 6. Selective loss of anti-cancer cell growth efficiency of Pro-haloacetate-NPs against non-cancerous cell of breast origin (MCF-10A) compared to cancer cell (MCF-7) of same origin.

Figure 6

Bright field imaging performed on (A) MCF10A cells post 48 h treatment with (B) Lipid-NPs; (C) Pro-DCA-NPs; (D) Pro-MCA-NPs; (E) Pro-DBA-NPs; (F) DCA; (G) MCA and (H) DBA at a concentration of 100 μM revealed no significant loss of cell growth density. (I) A comparative cell growth inhibition study in MCF-7 and MCF-10A cells treated with a concentration of 100 μM of DCA, MCA and DBA in free or form of Pro-haloacetate-NPs supporting biostatistically significant low effective toward MCF-10A cells compared to MCF-7 cells by p < 0.01. Propidium iodide incorporation study on (J) MCF-10A and treated with (K) Pro-DCA-NP; (L) Pro-MCA-NP and (M) Pro-DBA-NP with a haloacetate concentration of 100 μM for 48 h.