Table 2. Comparative profile of parental and placental CNVs. Data are given as means (medians), except when indicated otherwise. All, pooled duplication and deletion CNVs; n.a, not applicable; n.s, non-significant.

		Parental blood DNA (n = 93)	Placental DNA (n = 57)	Placental/Parental genome ratio	Wilcoxon rank sum test P-value
Number of CNVs per sample	All	9.5 (9.0)	28.5 (23.0)	3.0 (2.6)	<2.2 × 10−16
	Duplication	2.7 (3.0)	15.3 (12.0)	5.7 (4.0)	<2.2 × 10−16
	Deletion	6.8 (7.0)	13.2 (9.0)	1.9 (1.3)	5.6 × 10−5
Cumulative span of all CNVs per sample, Mb	All	0.8 (0.6)	3.6 (2.4)	4.5 (4.0)	9.1 × 10−14
	Duplication	0.5 (0.3)	2.0 (1.4)	4.0 (4.7)	7.6 × 10−13
	Deletion	0.3 (0.3)	1.5 (0.7)	5.0 (2.3)	1.1 × 10−7
CNV length across samples, kb	All	87.8 (23.0)	124.7 (70.4)	1.4 (3.1)	<2.2 × 10−16
	Duplication	183.8 (68.3)	130.8 (74.9)	0.7 (1.1)	n.s
	Deletion	49.8 (16.5)	117.6 (63.8)	2.4 (3.9)	<2.2 × 10−16
CNV size range, kb	All	0.3; 2392.4	0.3; 1814.4	n.a	n.a
	Duplication	2.2; 2392.4	2.2; 1814.4	n.a	n.a
	Deletion	0.3; 1629.9	0.3; 1480.7	n.a	n.a
Ratio (loss/gain)		2.5 (2.3)	0.9 (0.8)	0.4 (0.3)	2.9 × 10−14