Table 4. Imprinted genes disrupted by placental CNVs. Data modified from http://www.geneimprint.com/; * from Court et al. 2014. SGA, small-for-gestational age; GD, gestational diabetes; norm, normal term; PE, preeclampsia; LGA, large-for-gestational age.
| Gene | Location | Status | Expressed Allele | No of carriers | Groups |
|---|---|---|---|---|---|
| Genes disrupted by somatic duplication CNVs | |||||
| ALDH1L1 | 3q21.3 AS | Predicted | Maternal | 3 | SGA, GD, norm |
| CTNNA3 | 10q22.2 AS | Provisional Data | Maternal | 5 | 2 GD, 1 PE, SGA, norm |
| CYP1B1 | 2p21 AS | Predicted | Paternal | 3 | 2 PE, 1 GD |
| DVL1 | 1p36 AS | Predicted | Maternal | 1 | LGA |
| FGFRL1 | 4p16 | Predicted | Maternal | 1 | norm |
| HOXA11 | 7p15-p14 AS | Predicted | Maternal | 1 | norm |
| HOXA2 | 7p15-p14 AS | Predicted | Maternal | 1 | norm |
| HOXA3 | 7p15-p14 AS | Predicted | Maternal | 1 | norm |
| HOXA4 | 7p15-p14 AS | Predicted | Maternal | 1 | norm |
| HOXA5 | 7p15-p14 AS | Predicted | Maternal | 1 | norm |
| HOXC4 | 12q13.3 | Predicted | Maternal | 1 | norm |
| HOXC9 | 12q13.3 | Predicted | Maternal | 1 | norm |
| KCNQ1 | 11p15.5 | Imprinted | Maternal | 1 | norm |
| KCNQ1OT1 | 11p15 | Imprinted | Paternal | 1 | norm |
| NTM | 11q25 | Imprinted | Maternal | 1 | SGA |
| PEX10 | 1p36.32 AS | Predicted | Maternal | 2 | LGA |
| PKP3 | 11p15 | Predicted | Maternal | 1 | norm |
| PRDM16 | 1p36.23-p33 | Predicted | Paternal | 2 | LGA |
| SLC22A3 | 6q26-q27 | Imprinted | Maternal | 6 | 2 PE, norm, 1 LGA, GD |
| TP73 | 1p36.3 | Imprinted | Maternal | 2 | 1 LGA, norm |
| WDR27 | 6q27 | Provisional Data* | Paternal | 1 | SGA |
| Genes disrupted by somatic deletion CNVs | |||||
| FAM59A | 18q12.1 AS | Predicted | Paternal | 3 | LGA, PE, norm |
| NTM | 11q25 | Imprinted | Maternal | 1 | PE |
| SNRPN | 15q11.2 | Imprinted | Paternal | 2 | norm |
| Genes disrupted by inherited duplication CNVs | |||||
| NKX6-2 | 10q26 AS | Predicted | Maternal | 1 | norm |
| Genes disrupted by inherited deletion CNVs | |||||
| CTNNA3 | 10q22.2 AS | Provisional Data | Maternal | 1 | LGA |
| DGCR6 | 22q11.21 | Imprinted | Random | 1 | norm |