Figure 4.

Individual effects on serum LH and FSH during 8‐h infusions of vehicle and SC kisspeptin‐54 for each participant. Individual time profiles from each participant 1–4 are presented showing the effects on serum LH (a–d) and FSH (e–h) during infusions of vehicle and SC kisspeptin‐54 0·1, 0·3 and 1·0 nmol/kg/h in healthy women during the early follicular phase of the menstrual cycle. Infusions started at t = 0 min and continued for 8‐h until t = 480 min, 10 minutely blood sampling was conducted from t = 0 min. Black circles, vehicle; green circles, kisspeptin‐54 0·1 nmol/kg/h; blue circles, kisspeptin‐54 0·3 nmol/kg/h; red circles, kisspeptin‐54 1·0 nmol/kg/h.