Table 2.

Effects of baseline oestradiol on LH response to kisspeptin‐54 administration. Linear regression analysis was used to determine whether there was an association between baseline oestradiol and the LH response to SC kisspeptin‐54 at 3 doses (0·1, 0·3 and 1·0 nmol/kg/h) and vehicle, when administered to healthy women in the early follicular phase of the menstrual cycle. The regression coefficients and confidence intervals presented represent the change in mean LH for a 100pmol/l increase in baseline oestradiol

Group	Coefficient (95% CI)	P‐value
Vehicle	−0·25 (−0·72, 0·23)	0·26
0·1 nmol/kg/h kisspeptin‐54	−1·75 (−4·85, 1·36)	0·24
0·3 nmol/kg/h kisspeptin‐54	0·83 (0·12, 1·53)	0·03
1·0 nmol/kg/h kisspeptin‐54	1·00 (0·11, 1·89)	0·03