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. 2016 Jun 21;6:28278. doi: 10.1038/srep28278

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For univariate Cox regression, the summary relative risk was 5.31 (95% CI, 1.69 to 16.70) and test of heterogeneity I² = 0% (P = 0.37) (A); for multivariate Cox regression, the summary relative risk was 2.96 (95% CI, 1.38 to 6.34) and test of heterogeneity I² = 0% (P = 0.61) (B). The combined analysis showed that Non-OPR was statistically associated with recurrence.