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. 2016 Jun 21;6:28280. doi: 10.1038/srep28280

Table 1. Patient characteristics.

Characteristic n CDS (%) RT (%) CDS + RT (%) None (%) P-value
Year of diagnosis
 1988–1992 514 67 (15.7) 288 (6.0) 55 (6.5) 104 (3.4) <0.001
 1993–1997 668 68 (16.0) 406 (8.5) 55 (6.5) 139 (4.5)  
 1998–2002 1755 111 (26.1) 898 (18.8) 204 (24.1) 542 (17.7)  
 2003–2007 2854 102 (23.9) 1489 (31.1) 258 (30.5) 1005 (32.8)  
 2008–2012 3334 78 (18.3) 1705 (35.6) 275 (32.5) 1276 (41.6)  
Race
 Black 1016 49 (11.5) 645 (13.5) 59 (7.0) 263 (8.6) <0.001
 White 7621 356 (83.6) 3832 (80.1) 750 (88.5) 2683 (87.5)  
 Other 488 21 (4.9) 309 (6.5) 38 (4.5) 120 (3.9)  
Age
 ≤60 3515 159 (37.3) 1773 (37.0) 419 (49.5) 1164 (38.0) <0.001
 >60 5610 267 (62.7) 3013 (63.0) 428 (50.5) 1902 (62.0)  
Sex
 Male 7486 349 (81.9) 3867 (80.8) 736 (86.9) 2534 (82.6) <0.001
 Female 1639 77 (18.1) 919 (19.2) 111 (13.1) 532 (17.4)  
Tumor histology
 Squamous 2757 111 (26.1) 1769 (37.0) 207 (24.4) 670 (21.9) <0.001
 Adenocarcinoma 5406 270 (63.4) 2574 (53.8) 543 (64.1) 2019 (65.9)  
 Other 962 45 (10.6) 443 (9.3) 97 (11.5) 377 (12.3)  
Tumor location
 Upper thoracic 483 8 (1.9) 340 (7.1) 27 (3.2) 108 (3.5) <0.001
 Middle thoracic 1647 62 (14.6) 1029 (21.5) 110 (13.0) 446 (14.5)  
 Lower thoracic 6995 356 (83.6) 3417 (71.4) 710 (83.8) 2512 (81.9)  
Grade (n = 7653)
 G1 270 14 (3.6) 143 (3.6) 24 (3.2) 89 (3.5) 0.271
 G2 2826 138 (35.8) 1522 (38.0) 287 (38.4) 879 (34.9)  
 G3-4 4557 234 (60.6) 2339 (58.4) 436 (58.4) 1548 (61.5)  

CDS, cancer-directed surgery; RT, radiotherapy; G1, well differentiated; G2, moderately differentiated; G3, poorly differentiated; G4, undifferentiated.