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. 2016 Jun 21;13:157. doi: 10.1186/s12974-016-0624-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The incidence of secondary insults, expressed as proportion of good monitoring time (GMT) is described in each outcome group (a). Difference among groups was significant for raised ICP, hypotension, low CPP, and hypoxia insults (ANOVA, p < 0.01). Post-hoc analysis revealed that differences were significant between brain death and both favorable and unfavorable outcome (*p < 0.05). Data are expressed as mean and standard error. ICP intracranial pressure, CPP cerebral perfusion pressure. b Boxplots of IL-6 level in each outcome group. Difference among groups was significant (ANOVA, p < 0.001). Post-hoc analysis revealed that differences were significant between brain death and both favorable and unfavorable outcome (*p < 0.05). Circles represent outliers