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. 2016 Jun 21;8:70. doi: 10.1186/s13148-016-0238-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — DNAm changes in IUGR twins in ZNF300 promoter. Methylation levels in IUGR twins (orange circles) and unaffected co-twins (blue crosses) are shown, arranged vertically for each CpG in the region spanning the promoter of the ZNF300 gene transcript. The mean methylation levels are shown for the IUGR cohort (red line) and controls (blue line). The top seven CpGs with methylation change above 10 % comprise the DMR (red box), which also corresponds to the wider gap between the red and blue lines