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. 2016 Jun 21;8:70. doi: 10.1186/s13148-016-0238-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — CpG sites used for functional enrichment analysis. Only the CpGs that have a DNAm difference at least 10 % in IUGR twins were considered. A set of 296 CpGs (numbers in red) was selected as the sites that were identified by limma regression analysis after accounting for confounding effects and also passed at least one of the non-parametric tests for IUGR association. The right Venn diagram shows the number of genes matching each criteria of significance, where 172 genes comprise the set tested for functional enrichment