Table 3.

Studies Comparing CTAC- and MRAC-Derived Standardized Uptake Values in Normal Structures

	Drzezga (8)	Heusch (28)	Kershah (27)	Pace (9)	Current study
Primary malignancy	Various	Various	Various	Breast	Breast
Number of patients	32	25	40	36	35
Injection-PET/CT interval (mean ± SD)	86 ± 8 min	60 min	66 ± 7 min	60 ± 10 min	60 ± 14 min
PET accumulation time per station (PET/CT)	2 min	2 min	1.5–2 min	1.5 min	2 min
PET/MRI manufacturer	Siemens	Siemens	Philips	Siemens	Siemens
Injection-PET/MRI interval (mean ± SD)	140 ± 24 min	152 ± 42 min	117 ± 15 min	148 ± 22 min	167 ± 36 min
PET accumulation time per station (PET/MRI)	4 min	8 min	2–2.5 min	4 min	6 min
MRAC segmentation classes	4	4	3	4	4
SUV relationships*,†
Blood pool
Correlation	NE	Weak	Moderate	NE	Weak
Difference	NE	MRAC<CTAC	MRAC<CTAC	NE	MRAC<CTAC
Bone
Correlation	Moderate (mean)	Moderate	Strong	NE	Moderate
Difference	MRAC<CTAC	MRAC<CTAC (max)	MRAC>CTAC	NE	MRAC<CTAC
Lung
Correlation	Moderate (mean)	Weak	Strong (max)	Moderate	Moderate (mean)
Difference	MRAC<CTAC	MRAC<CTAC	No difference	MRAC<CTAC	MRAC<CTAC
Liver
Correlation	Moderate (mean)	Strong (mean)	Moderate	Moderate	Moderate (max)
Difference	MRAC<CTAC	MRAC<CTAC	MRAC<CTAC (mean)	MRAC<CTAC	MRAC<CTAC
Myocardium
Correlation	NE	Strong	Strong	Strong	Strong
Difference	NE	MRAC>CTAC (max)	MRAC>CTAC	MRAC>CTAC	MRAC>CTAC
Noncardiac muscle
Correlation	Weak (mean)	Moderate (max)	Moderate	Moderate	Moderate (mean)
Difference	MRAC<CTAC	MRAC<CTAC	MRAC>CTAC (max)	MRAC<CTAC	No difference
Fat
Correlation	NE	Moderate (mean)	Moderate	NE	Weak
Difference	NE	MRAC<CTAC	No difference	NE	MRAC<CTAC

^*SUVmax and SUVmean unless indicated.

^†Correlation ρ> 0.70 was considered strong, 0.30 ≤ ρ≤ 0.70 moderate, and ρ< 0.30 weak.

NE, not evaluated.