Table 1.

Frequency spectrum of hTERT promoter mutations across diverse cancer types

Cancer type	Mutation frequency (%)	Reference
Bladder carcinoma	47–85	[100]
Renal pelvic carcinoma	60–64	[101]
Urothelial carcinoma	47	[102]
Hepatocellular carcinoma	24–59	[6, 103]
Melanoma	67–85	[3]
Skin basal cell carcinoma	39–74	[104]
Thyroid cancer (papillary and poorly differentiated carcinomas)	50–52	[105]
Myxoid liposarcoma	74–79	[106]
Glioblastoma	28–84	[6, 48]
Medulloblastoma	19–42	[107]
Oligoastrocytoma Oligodendroglioma	25–53 72	[6, 107] [44]
Breast cancer, colorectal cancer, medullary thyroid carcinoma, ovarian cancer, esophageal adenocarcinoma, acute myeloid leukemia, chronic lymphoid leukemia, pancreatic cancer, prostate cancer, testicular carcinoma, uterine cervix cancer	0–5	[48, 104]