Table 3.
Least square means, heritabilities, litter effects, and phenotypic standard deviations (SD) of responses to infection with the NVSL and KS06 isolates
| Trait | LS meansa,b | P valuec | Heritabilityb,d | Litterb,d | Phenotypic sdb,d | ||||
|---|---|---|---|---|---|---|---|---|---|
| NVSL (se) | KS06 (se) | NVSL (se) | KS06 (se) | NVSL (se) | KS06 (se) | NVSL | KS06 | ||
| WG | 15.8 (1.1) | 19.5 (1.4) | 0.076 | 0.33 (0.06) | 0.31 (0.09) | 0.07 (0.03) | 0.03 (0.04) | 3.90 | 3.91 |
| VL | 110.5 (1.4) | 95.0 (1.6) | <0.001 | 0.31 (0.06) | 0.51 (0.09) | 0.24 (0.03) | 0.01 (0.04) | 7.90 | 7.46 |
| TP | 7.0 (0.4) | 9.5 (0.4) | 0.004 | 0.22 (0.05) | 0.20 (0.09) | 0.16 (0.03) | 0.10 (0.05) | 1.36 | 1.54 |
| PV | 6.6 (0.1) | 5.8 (0.1) | <0.001 | 0.17 (0.05) | 0.45 (0.08) | 0.27 (0.04) | 0.00 (0.00) | 0.40 | 0.41 |
| Tmax | 15.4 (0.5) | 19.3 (0.6) | 0.002 | 0.21 (0.05) | 0.16 (0.09) | 0.15 (0.03) | 0.14 (0.05) | 2.38 | 2.73 |
| Vmax | 0.30 (0.02) | 0.22 (0.02) | 0.033 | 0.09 (0.05) | 0.26 (0.09) | 0.08 (0.03) | 0.01 (0.04) | 0.08 | 0.05 |
WG weight gain (kg), VL viral load (area under the Wood’s curve of log10 serum viremia from 0 to 21 days post-infection; viremia * days), TP time to peak viremia (days), PV peak viremia (log10 serum viremia), Tmax time to maximal rate of viremia decay (days), Vmax maximal rate of viremia decay (log10 serum viremia/day), se standard error
aFull G-matrix used
bEstimates were obtained by fitting isolate in the model and only included trials in which pigs from the same genetic background were infected with both NVSL and KS06
cP value for the difference in the estimated least square (LS) means between NVSL and KS06
dEstimates were obtained by using the full G-matrix; NVSL and KS06 estimates were estimated separately, and included all animals infected with that isolate, except trial 13