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. 2016 Jun 20;48:43. doi: 10.1186/s12711-016-0222-0

Table 4.

Estimates of genetic correlations [genet cor. (standard errors)] between response to infection with the NVSL versus KS06 isolates and using different relationship matrices

Trait Full (G) Block diagonal (G B) Paired block diagonal (G p)
Heritability Genet cor. Heritability Genet cor. Heritability Genet cor.
NVSL KS06 NVSL KS06 NVSL KS06
VL 0.32 (0.06) 0.53 (0.07) 0.86 (0.19) 0.40 (0.06) 0.53 (0.08) 0.51 (0.24) 0.51 (0.08) 0.54 (0.09) 0.57 (0.22)
WG 0.33 (0.05) 0.30 (0.09) 0.86 (0.27) 0.37 (0.06) 0.32 (0.10) 0.96 (0.34) 0.41 (0.08) 0.38 (0.11) 0.90 (0.31)
TP 0.22 (0.05) 0.21 (0.09) 0.25 (0.33) 0.28 (0.06) 0.28 (0.10) 0.40 (0.36) 0.32 (0.08) 0.30 (0.12) 0.43 (0.36)
PV 0.17 (0.05) 0.46 (0.07) 0.94 (0.28) 0.23 (0.06) 0.43 (0.08) 0.94 (0.33) 0.29 (0.07) 0.42 (0.09) 0.91 (0.30)
Tmax 0.21 (0.05) 0.14 (0.09) 0.82 (0.53) 0.26 (0.06) 0.16 (0.10) 0.86 (0.59) NEa NE NE
Vmax 0.10 (0.05) 0.25 (0.09) 0.63 (0.51) 0.13 (0.05) 0.22 (0.10) 0.32 (0.67) 0.06 (0.06) 0.23 (0.12) 0.41 (0.92)

G = full G-matrix with all relationships included; G B = block diagonal G-matrix, with the relationships between animals from different genetic backgrounds set to zero; G p = paired block diagonal G-matrix, with the relationships between animals from different genetic backgrounds set to zero, and only included trials in which pigs from the same genetic background were infected with both NVSL and KS06

WG weight gain (kg), VL viral load (area under the Wood’s curve of log10 serum viremia from 0 to 21 days post infection; viremia * days), TP time to peak viremia (days), PV peak viremia (log10 serum viremia), Tmax time to maximal rate of viremia decay (days), Vmax maximal rate of viremia decay (log10 serum viremia/day)

aNE: were not estimated because the model did not achieve convergence in ASReml