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. 2016 Jun 21;35:100. doi: 10.1186/s13046-016-0379-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Knockdown of TRIM11 reduced the proliferation of lung cancer cells. a, b CCK-8 assay results of A549 and NCI- H446 cells at 0 h, 24 h, 48 h and 72 h after TRIM11 expression was inhibited by siRNA3 transfection. c, d Expression of PCNA and Cyclin D1 was evaluated by Western blot. Quantification (bottom panel) based on at least 3 independent experiments was shown. ***P < 0.001 versus NC