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. 2016 Jun 21;15:112. doi: 10.1186/s12934-016-0511-x

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Synthesis ratios of a virtual mutant lacking allosteric reactions to WT. The x-axis represents the reaction name and the y-axis represents the synthesis ratio. a Pfk. b Pyk. c Mez (Mez more then 1.4). d Fbp. e Icl (Icl and MS more then 2). f Ppc