Table 2.

Ranking of the critical parameters

Rank	Parameter	Sensitivity
1	$v_{Pts4}^{\text{max}}$	3.0405
2	$v_{Nonpts}^{\text{max}}$	0.8187
3	$v_{G6pdh}^{\text{max}}$	−0.4044
4	k Pfk_cat	0.3947
5	k Mdh1_cat	0.2211
6	k Fbp_cat	−0.1907
7	k Ppc_cat	0.1620
8	k Sdh1_cat	0.1179
9	k Pdh_cat	0.1154
10	k Cs_cat	0.1032
11	k Pyk_cat	−0.0576
12	$v_{Pta}^{\text{max}}$	0.0473
13	$v_{6pgdh}^{\text{max}}$	0.0408
14	k Mez_cat	−0.0393
15	$v_{Ack}^{\text{max}}$	0.0360
16	k Fum1_cat	0.0298
17	$v_{Edd}^{\text{max}}$	−0.0266
18	k Gapdh_cat	0.0248
19	k Mdh2_cat	0.0135
20	$v_{Ru5p}^{\text{max}}$	0.0090
21	k Pck_cat	−0.0079
22	k Pps_cat	0.0071
23	k Acs_cat	−0.0066
24	k Fba_cat	0.0061
25	$v_{TktA}^{\text{max}}$	0.0058
26	k Fum2_cat	0.0056
27	$v_{TktB}^{\text{max}}$	0.0039
28	$v_{R5PI}^{\text{max}}$	−0.0021
29	$v_{Eda}^{\text{max}}$	−0.0021
30	$v_{Pgi}^{\text{max}}$	0.0016
31	k Sdh2_cat	0.0007
32	$v_{Tal}^{\text{max}}$	0.0007
33	k Icdh_cat	0.0004
34	$k_{Glk\_cat}$	0.0002
35	k αkgdh_cat	0.0002
36	$v_{Pgl}^{\text{max}}$	−9.54E−07
37	k Ms_cat	6.97E−07
38	k Icl_cat	6.39E−07

The sensitivities were sampled at 6 h. The kinetic parameters were sorted according to their absolute values