Table 1.

SJS/TEN in the Japanese Adverse Drug Event Report database (April 2004–April 2015)

	Gender	Total			Allopurinol			Loxoprofen			Acetaminophen			Carbamazepine			Lamotrigine
		Reported cases		Reporting ratio (%)	Reported cases		Reporting ratio (%)	Reported cases		Reporting ratio (%)	Reported cases		Reporting ratio (%)	Reported cases		Reporting ratio (%)	Reported cases		Reporting ratio (%)
		SJS or TEN	Total		SJS or TEN	Total		SJS or TEN	Total		SJS or TEN	Total		SJS or TEN	Total		SJS or TEN	Total
Total		6568	353988	1.86	544	2642	20.59	525	4714	11.14	498	1925	25.87	420	4517	9.30	403	2375	16.97
Stratified by agea
≤19 years	M	388	12982	2.99	1	9	11.11	14	69	20.29	87	325	26.77	35	345	10.14	3	76	3.95
	F	295	12088	2.44	0	7	0.00	12	80	15.00	83	262	31.68	17	265	6.42	17	144	11.81
20-39 years	M	470	13842	3.40	22	98	22.45	89	368	24.18	32	129	24.81	41	369	11.11	32	191	16.75
	F	791	20302	3.90	11	39	28.21	100	555	18.02	101	298	33.89	54	481	11.23	82	554	14.80
40-59 years	M	723	36749	1.97	80	454	17.62	60	606	9.90	33	155	21.29	40	630	6.35	60	318	18.87
	F	796	36347	2.19	39	126	30.95	90	631	14.26	58	205	28.29	49	495	9.90	76	331	22.96
60-79 years	M	1192	86098	1.38	154	902	17.07	88	991	8.88	45	218	20.64	77	761	10.12	25	170	14.71
	F	1099	71275	1.54	106	420	25.24	53	889	5.96	45	198	22.73	76	569	13.36	53	251	21.12
≥80 years	M	227	18393	1.23	35	218	16.06	6	169	3.55	3	39	7.69	5	121	4.13	10	27	37.04
	F	383	22610	1.69	89	266	33.46	9	300	3.00	8	66	12.12	10	153	6.54	6	39	15.38
Subtotal		6364	330686	1.92	537	2539	21.15	521	4658	11.19	495	1895	26.12	404	4189	9.64	364	2101	17.33

^aCompleted with age and gender