Fig. 2.

Time course of CNP agglomerate uptake. The amount of by BAL recovered cells showing inclusions of CNP agglomerates was quantified by the examination of cytospins from mice 3 to 24 h after particle instillation. Particle uptake was exclusively observed for macrophages but and no agglomerates we observed in polymorphonuclear, neutrophilic granulocytes (a). Free, not cell-associated particle agglomerates are predominantly detected at the early time points, till 12 h after exposure. Figure 2b shows the time course of the particle uptake given as the percentage of particle laden macrophages