Table 1.
Study participants
| Characteristics | Values for indicated group [median (IQR)] or individual values | ||||||
|---|---|---|---|---|---|---|---|
| Control | Asymptomatic | Acute uncomplicated | |||||
| Sub-microscopic | Sub-microscopic | Patent | Patent | Malaria | Malaria | ||
| P. falciparum | P. vivax | P. falciparum | P. vivax | P. falciparum | P. vivax | ||
| No. of subjects | |||||||
| Total | 83 | 19 | 15 | 17 | 19 | 6 | 8 |
| Female/male | 46/37 | 10/9 | 8/7 | 12/5 | 14/5 | 4/2 | 5/3 |
| Papuan/non-Papuan | 29/54 | 9/10 | 9/6 | 7/10 | 14/5 | 6/0 | 6/2 |
| Age (years) | 30 (25–37) | 31 (26–36) | 28 (21–31) | 28 (24–36) | 32 (30–36) | 21 (20–24)* | 27 (23–36) |
| Time resident in area (years) | 12 (5–20) | 10 (6–18) | 9 (5–25) | 10 (5–22) | 10 (2–15) | NA | NA |
| No. of parasites/µl | ND | ND | ND | 294 (82–2065) | 210 (89–696) | 24,725 (10,734–57,274)# | 58,341 (10,778–89,678)# |
| Lymphocyte count (109/l) | 2.5 (2.2–3.1) | 2.2 (1.5–2.6)a | 2.6 (2.2–3.7) | 2.5 (1.7–2.8) | 2.5 (1.8–3.7) | 1.4 (0.7–1.6)** | 1.0 (0.7–1.2)*** |
| Monocyte count (109/l) | 0.5 (0.4–0.6) | 0.4 (0.3–0.7) | 0.6 (0.4–0.7) | 0.6 (0.5–0.7)a | 0.5 (0.3–0.8) | 0.7 (0.6–0.7)* | 0.9 (0.4–1.4)a |
IQR interquartile range, ND no parasite detected by microscopy, NA data not available
Significantly different to control, Kruskal–Wallis test with Dunn’s multiple comparisons
* P < 0.05
** P < 0.005
*** P < 0.0005
#Significantly different to species-matched patent infection, Kruskal–Wallis test with Dunn’s multiple comparisons (P < 0.0005)
aSignificantly different to control, Mann–Whitney U test (P < 0.05)