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. 2016 Jun 20;213(6):705–718. doi: 10.1083/jcb.201512022

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© 2016 Demonbreun et al.

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Figure 10. — Model of membrane repair. Upon plasma membrane injury, repair proteins localize to the site of damage and actin reorganizes, facilitating membrane repair. Annexins A1, A2, and A6 form a repair cap at the membrane lesion. Dysferlin (DYSF), MG53, BIN1, and EHD participate in forming a shoulder that abuts this repair cap. PIP2 and PS localize adjacent to the repair cap at the shoulder.