[11C]WAY100635 binding potential (BPF) estimates for the 5-HT1A receptor in male control and male MDD subjects across 13 regions of interest. Thin-capped vertical bars represent weighted standard errors. Raphe nuclei (RN), ventral prefrontal cortex (VPFC), medial prefrontal cortex (MPFC), dorsolateral prefrontal cortex (DLPFC), anterior cingulate cortex (ACN), cingulate (posterior) cortex (CIN), amygdala (AMY), hippocampus (HIP), parahippocampal gyrus (PHG), insular cortex (INS), temporal cortex (TEM), parietal cortex (PAR), and occipital cortex (OCC).