Figure 2.

Extra-Amygdaloid Granger Causality Paths: CeA. (a) Non-ELS demonstrated a concise OFC-derived path that predicted bilateral CeA response. In contrast, the ELS group demonstrated a much more complex CeA-dominant pattern in which right CeA activity predicted activity in multiple cortical regions including bilateral DLPFC, BA 11, BA32, 25 and 24, and hippocampus. In addition right DLPFC predicted bilateral CeA, while left DLPFC predicted left CeA. Left hippocampus predicted bilateral CeA. p-values are FDR-corrected. Abbreviations: BA, Brodmann's Area; CeA, central nucleus; DLPFC, dorsal lateral prefrontal cortex; ELS, early life stress; FDR, false discovery rate; OFC, orbitofrontal cortex.