Figure 5.

Granger Causality Paths and Implicit Modulation of Emotion. As a measure of implicit regulation of emotion, we performed correlation analysis between connectivity coefficients for intra-amygdaloid and extra-amygdaloid lateral/medial paths with individual threat ratings for the UCS trials. (a) A negative causal path from right BA 11 (OFC) to left BLA was associated with less perceived threat in non-ELS, p<0.01 (b) Similarly, a negative causal path from left BA32 to left BLA was associated with less perceived threat in the non-ELS group, p<0.05 (c) A positive causal path from right hippocampus to right BLA was associated with less perceived threat in the non-ELS group, p<0.05 and (d) A positive causal path from right BLA to left CeA was associated with less perceived threat within the ELS group, p<0.05. Abbreviations: BA, Brodmann's Area; BLA, basolateral; CeA, central nucleus; ELS, early life stress; OFC, orbitofrontal cortex; UCS, unconditioned stimulus.