. 2016 Jun 18;22:2086–2096. doi: 10.12659/MSM.895390

Table 1.

Baseline characteristics and methodological quality of all included studies.

First author	Year	Ethnicity	Disease	Number		Gender (M/F)		Age (years)		Genotype method	Gene	SNP	NOS score
First author	Year	Ethnicity	Disease	Case	Control	Case	Control	Case	Control	Genotype method	Gene	SNP	NOS score
Papagianni A [30]	2013	Caucasians	Children	53	45	26/27	–	5.9±3.9	–	PCR-RFLP	CD16	158 F>V	6
Nourse JP [29]	2012	Caucasians	Total	100	100	–	–	51 (18~85)	39 (21~66)	AS-PCR	CD16	158 F>V	6
Eyada TK [20]	2012	Africans	Children	92	90	44/48	40/50	8.3±4.5	6.2±3.5	PCR-RFLP	CD16	131 H>R	8
Eyada TK [20]										AS-PCR	CD16	158 F>V
Amorim DM [10]	2012	Caucasians	Children	39	78	18/21	36/42	7.3±3.2	5.4±4.0	PCR-RFLP	CD16	158 F>V	7
Amorim DM [10]												131 H>R
Breunis WB [21]	2008	Caucasians	Adult	44	100	7/37	–	–	–	MLPA assay	CD32	131 H>R	6
Breunis WB [21]			Children	72	100	35/37	–	–	–	MLPA assay	CD32	131 H>R	6
Wang JH [31]	2007	Asians	Total	74	111	22/52	45/66	34.5±13.3	39.0±16.3	AS-PCR	CD16	158 F>V	7
Carcao MD [26]	2003	Caucasians	Children	98	130	46/52	–	0.5±16.9	–	PCR-RFLP	CD32	158 F>V	8
Carcao MD [26]												131 H>R
Fujimoto TT [27]	2001	Asians	Total	104	59	28/76	30/29	26	54.2	PCR-RFLP	CD32	158 F>V	8
Fujimoto TT [27]												131 H>R
Foster CB [22]	2001	Caucasians	Children/chronic	36	218	–	–	–	–	PCR-RFLP	CD32	158 F>V	6
Foster CB [22]												131 H>R
Williams Y [32]	1998	Caucasians	Total	29	61	30/60	10/19	7~75	20~55	AS-PCR	CD32	131 H>R	6

M – male; F – female; SNP – single nucleotide polymorphism; NOS – Newcastle-Ottawa Scale; PCR-RFLP – polymerase chain reaction-restriction fragment length polymorphism; AS-PCR – allele-specific PCR, MLPA multiplex ligation-dependent probe amplification.