Figure 3.
This plot shows the estimated cumulative probability of time to progress from early-stage to moderate-stage dementia classification based on neuropathologic classification at autopsy: no significant neuritic plaque (NP) or cerebral amyloid angiopathy (CAA) burden (CAA−/NP− or CAA+/NP−, blue line), no significant CAA burden but significant NP burden (CAA−/NP+, green line), significant CAA and NP burden (CAA+/NP+, red line). The light gray horizontal line at denotes at least 50% of individuals transitioning to moderate-stage dementia.