Table 2.
Group demographics for the sample.
| CAA− / NP− n=257 |
CAA− / NP+ n=651 |
CAA+ / NP− n=37 |
CAA+ / NP+ n=469 |
Number of missing values |
sig | |
|---|---|---|---|---|---|---|
| Age at Enrollment, y |
83.9 (8.6) | 80.7 (8.4) | 85.6 (7.5) | 79.5 (8.2) | 0 | F(3,1410)=18. 9, p<0.001 |
| Age at Death, y | 87.0 (8.8) | 84.0 (8.3) | 90.0 (7.5) | 83.0 (8.1) | 0 | F(3,1410)=17. 8, p<0.001 |
| Female, n(%) | 132 (51.4) |
308 (47.3) |
18 (48.7) | 212 (45.2) | 0 | X2(3)=2.6, p=0.47 |
| Education, y | 15.1 (3.3) | 15.2 (3.1) | 15.1 (2.8) | 14.9 (3.3) | 10 | F(3,1401)=0.8 , p=0.48 |
| Race, n(%) | 0 | |||||
| White | 246 (95.7) |
621 (95.4) |
32 (86.5) | 444 (94.7) | -- | X2(3)=6.2, p=0.10 |
| Black | 6 (2.3) | 24 (3.7) | 3 (8.1) | 20 (4.3) | -- | |
| Other | 5 (2.0) | 6 (0.9) | 2 (5.4) | 5 (1.0) | -- | |
| Hispanic Ethnicity, n(%) |
12 (4.7) | 23 (3.5) | 1 (2.7) | 20 (4.3) | 5 | X2(3)=0.9, p=0.82 |
| Hypertension, n(%) |
146 (57.5) |
320 (49.2) |
21 (56.8) | 217 (46.4) | 4 | X2(3)=9.0, p=0.03 |
| Hypercholesterole mia, n(%) |
115 (45.1) |
284 (43.9) |
22 (61.1) | 215 (46.2) | 10 | X2(3)=4.3, p=0.23 |
| ApoE4 Carrier, n(%) |
43 (18.6) | 274 (49.4) |
17 (54.8) | 277 (69.1) | 195 | X2(3)=150.6, p<0.001 |
| CAA Classification at autopsy, n(%) |
0 | |||||
| None, Unknown |
185 (72.0) |
280 (43.0) |
-- | -- | -- | |
| Mild | 72 (28.0) | 371 (57.0) |
-- | -- | -- | |
| Moderate | -- | -- | 31 (83.8) | 282 (60.1) | -- | |
| Severe | -- | -- | 6 (16.2) | 187 (39.9) | -- | |
| CERAD neuritic plaque density, n(%) |
0 | |||||
| None | 159 (61.9) |
-- | 14 (37.8) | -- | -- | |
| Sparse | 98 (38.1) | -- | 23 (62.2) | -- | -- | |
| Moderate | -- | 194 (29.8) |
-- | 86 (18.3) | -- | |
| Frequent | -- | 457 (70.2) |
-- | 383 (81.7) | -- |
Values are frequencies or means (standard deviation), except when noted.