Table 3.
Group demographics for rate of progression from very mild (Clinical Dementia Rating = 0.5) to moderate dementia (Clinical Dementia Rating = 2).
| CAA− / NP− n=54 |
CAA− / NP+ n=139 |
CAA+ / NP− n=8 |
CAA+ / NP+ n=89 |
No. missing values |
Sig † | |
|---|---|---|---|---|---|---|
| Median Time of Dementia Progression, y |
4.5 † | 3.4 | 4.5† | 3.9 | -- | X2(2)=5.94, p=0.051 |
| Female, n (%) | 24 (44.4) | 58 (41.7) | 3 (37.5) | 33 (37.1) | 0 | X2(2)=0.75, p=0.69 |
| Education, y | 15.0 (3.4) | 15.7 (2.8) | 15.3 (2.3) | 15.6 (3.1) | 1 | F(2,354)=1.15, p=0.32 |
| Hypertension, n(%) | 32 (60.4) | 73 (52.5) | 4 (50.0) | 42 (47.2) | 1 | X2(2)=2.04, p=0.36 |
| Hypercholesterole mia, n(%) |
20 (37.7) | 60 (43.5) | 5 (71.4) | 50 (56.2) | 3 | X2(2)=4.38, p=0.11 |
| CAA Classification at autopsy, n (%) |
||||||
| None, Unknown | 39 (72.2) | 65 (46.8) | -- | -- | -- | |
| Mild | 15 (27.8) | 74 (53.2) | -- | -- | -- | |
| Moderate | -- | -- | 8 (100) | 52 (58.4) | -- | |
| Severe | -- | -- | 0 (0) | 37 (41.6) | -- | |
| CERAD neuritic plaque density, n(%) |
||||||
| None | 26 (48.1) | -- | 0 (0) | -- | -- | |
| Sparse | 28 (51.9) | -- | 8 (100) | -- | -- | |
| Moderate | -- | 51 (36.7) | -- | 25 (28.1) | -- | |
| Frequent | -- | 88 (63.3) | -- | 64 (71.9) | -- |
Values are frequencies or means (standard deviation).
†
CAA+ / NP− group was combined with CAA−/NP− due to few observations.