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. 2016 Mar;16(1):153–161. doi: 10.4314/ahs.v16i1.21

Table 1.

Characteristics of patients with carbapenem-non-susceptible Enterobacteriaceae

Patient
number/Isolatea 		Sexb/age Wardc Underlying diseased Invasive
procedure		 Type of
specimen
tested		 Infection due
to CPE		 Antibiotic therapy Outcome
1/KPN1 M/65
years		 Brain Hospital
ICU		 TBI Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Levofloxacin Alive
2/ECL1 M/24
years		 Orthopedics Tibia and fibula fracture Plate fixation Wound
secretion		 Wound
infection		 Lomefloxacin Alive
3/ECL2 M/78
years		 Department of
cardiovascular		 MI, hypertension, diabetes,
GCA		 None Tracheal
secretion		 Pneumonia Ceftizoxime Alive
4/KPN2 M/neonatal NICU Premature
infant, CHD, NRF, RDS,
HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Imipenem Alive
5/KPN3 M/neonatal NICU Premature infant, MODS,
NRF, RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Piperacillin/tazobactam Death
unrelated to
CPE
6/ECL3 F/62
years		 Brain Hospital
ICU		 ICH Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Ciprofloxacin Alive
7/KPN4 F/83
years		 Brain Hospital
ICU		 TBI Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Levofloxacin Alive
8/KOX1 F/54
years		 Orthopedics Right knee purulent
arthritis		 Arthroscopic
Surgery		 Wound
secretion		 Wound
infection		 Lomefloxacin Alive
9/KOX2 F/76
years		 Surgery ICU NRF, CHD, RA Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Moxifloxacin Death
unrelated to
CPE
10/KPN5 M/neonatal NICU Premature infant, NRF,
RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Meropenem Alive
11/KPN6 M/neonatal NICU Premature infant, NRF Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Imipenem, cefepime Alive
12/KPN7 M/neonatal NICU Premature infant, MODS,
asphyxia, NRF,
RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Cefoperazone/sulbactam Alive
13/KPN8 F/neonatal NICU Premature infant, MODS,
NRF, RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Cefoperazone/sulbactam,
cefepime		 Alive
14/KPN9 M/neonatal NICU Premature infant, MODS,
CHD, NRF, RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Imipenem, cefepime,
cefoperazone/sulbactam		 Alive
15/KPN10 M/neonatal NICU Asphyxia, NRF, RDS,
HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia None Alive
16/KPN11 M/neonatal NICU Premature infant, MODS,
RDS, HIE, IVH		 None Tracheal
secretion		 Pneumonia Piperacillin/tazobactam,
ceftriaxone		 Alive
17/KPN12 M/neonatal NICU Premature infant, NRF,
RDS		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Amoxicillin/sulbactam,
ceftriaxone		 Alive
18/KPN13 M/neonatal NICU Premature
infant, RDS, HIE		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Amoxicillin/sulbactam Death
unrelated to
CPE
19/KPN14 M/neonatal NICU Premature infant, MODS,
RDS		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Amoxicillin/sulbactam Alive
20/ECL4 F/2
years		 PICU CPR, NRF, convulsion Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Amikacin, ceftazidime,
cotrimoxazole		 Transferred
to other
hospitals
21/KPN15 M/neonatal Neonatology
department(1)		 NRF, MODS None Tracheal
secretion		 Pneumonia Meropenem,
piperacillin/tazobactam		 Alive
22/KPN16 F/neonatal NICU Fetal macrosomia, HIE,
MODS		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia None Alive
23/KPN17 F/neonatal NICU Premature infant, HIE,
NRF, MODS, CHD		 None Tracheal
secretion		 Pneumonia Piperacillin/tazobactam Alive
24/KPN18 M/neonatal NICU Premature infant, HIE None Tracheal
secretion		 Pneumonia Meropenem,
piperacillin/tazobactam		 Alive
25/KPN19 M/neonatal NICU HIE, asphyxia, NRF Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Meropenem Alive
26/KPN20 M/neonatal NICU Premature infant, HIE Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Ceftriaxone Alive
27/KPN21 M/neonatal NICU Premature infant, HIE None Tracheal
secretion		 Pneumonia Meropenem, Ceftriaxone Alive
28/KPN22 F/neonatal NICU Premature infant, HIE Mechanical
ventilation		 Tracheal
secretion		 Pneumonia None Alive
29/KPN23 M/neonatal NICU Premature infant,
asphyxia, RDS		 Mechanical
ventilation		 Tracheal
secretion		 Pneumonia Imipenem Alive
30/KPN24 F/neonatal Neonatology
department(2)		 Premature infant, HIE None Tracheal
secretion		 Pneumonia Meropenem Alive
a

KPN, Klebsiella pneumoniae; ECL, Enterobacter cloacae; KOX, Klebsiella oxytoca.

b

M, male; F, female.

c

TBI, traumatic brain injury; MI, myocardial infarction; GCA, gastric cardiac adenocarcinoma; CHD, congenital heart disease; NRF, neonatal respiratory failure; RDS, respiratory distress syndrome; HIE, hypoxic-ischemic encephalopathy; ICH, intracerebral hemorrhage; RA, rheumatoid arthritis; IVH, intraventricular hemorrhage; CPR, cardiopulmonary resuscitation.

d

NICU, neonatal intensive care units; PICU, pediatric intensive care unit.