Glucosamine and chondroitin sulphate (GlcN-CS) |
Increase collagen synthesis, ameliorate mechanical properties, organization of collagen bundles and resistence to fatigue, helpful in the management of pain. |
Vitamin C (Vit C) |
Stimulate hydroxyproline synthesis of procollagen, enhance angiogenesis and maturation of Col III to Col I fibers, anti-inflammatory and antioxidant effect. |
Collagen I (Col I) |
Increase mechanical properties, beneficial effects on collagen-rich tissues. |
L-arginine-α-keto-glutarate |
Substrate of NOS, increase NO levels and collagen synthesis. |
Curcumin |
Neoangiogenesis and apotosis inhibitor, antioxidant effect, stimulate tenocytes survival. |
Boswellic acid |
Elastase and 5-LO activity inhibition, reduce TNFα, IL-1, IL-2, IL-4, IL- 6 e INFγ levels. |
Methilsulfonilmethane (MSM) |
Analgesic, anti-inflammatory and antioxidant effects, reduce MDA and GSSG levels. |
Bromelain |
Decrease lymphocytes rolling, anti edema, antioxidant and immunosuppressive effects, reduce MDA levels. |