Table 1.

Network pathway annotation terms enriched in quiescence upregulated genes. Genes ≥5 fold up-regulated in response to quiescence induction were analyzed for enrichment of KEGG terms. The identified enriched pathway KEGG annotation terms (GeneSet) from network analyses are listed. The total number of genes from the network identified to be upregulated in response to quiescence and belonging to a specific pathway was identified. p-value (with 0 values equating to<0.0001) and false discovery rates (FDR) are presented. Nodes identify specific genes/proteins from our data sets present in the networks.

GeneSet	Genes From Network	p-value	FDR	Nodes
Complement and coagulation cascades	9	0	<1.000e-03	CFH,CFD,SERPING1,C3,C1R,BDKRB2,C1S,C2,CFB
Extracellular matrix organization	13	0	<5.000e-04	LTBP4,NCAM1,CTSK,VCAN,MFAP4,FMOD,LUM,DCN,BMP4,BMP2,TNXB,FBLN1,COL14A1
Staphylococcus aureus infection	7	0	<3.333e-04	CFH,CFD,C3,C1R,C1S,C2,CFB
Metabolism of xenobiotics by cytochrome P450	5	0.0003	2.73E-02	ADH1B,ADH1A,AKR1C2,AKR1C1,ALDH3A1
Pertussis	5	0.0003	2.32E-02	SERPING1,C3,C1R,C1S,C2
BMP receptor signaling	4	0.0003	1.97E-02	CHRDL1,BMP4,BMP2,CHRD
Complement cascade	7	0.0007	4.16E-02	CFH,CFD,C3,C1R,C1S,C2,CFB
Cadherin signaling pathway	5	0.0011	5.34E-02	CDH23,PCDHB5,PCDHB4,PCDHB14,PCDHB12
Wnt signaling pathway	8	0.0011	4.79E-02	CDH23,PCDHB5,PCDHB4,SMARCA5,PCDHB14,PCDHB12,SFRP2,SFRP4