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The modular domain organization of Sld3 is shown. The N-terminal domain (amino acids 1-115) binds to Sld7. The middle domain (amino acids 148-430) binds to Cdc45. The C-terminal domain (amino acids 511-668) binds to ssDNA, binds to Mcm3/Mcm5, and stimulates DDK phosphorylation of Mcm2.
