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. 2016 Jun 21;57(3):201–209. doi: 10.1093/jrr/rrv088

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© The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 4. — Histopathologic evaluation of right lung lobe tissues in control, 25 Gy, and 30 Gy groups at 22 weeks post irradiation. (A) Representative images of H&E and Masson's Trichrome stains of non-irradiated and irradiated right lungs. Note that the thickening of interlobular septa with collagenous tissue (arrows) was more severe in the 30 Gy group than in the 25 Gy group. Scale bar represents 1 mm (right bottom). (B) Quantitative fibrosis scores of non-irradiated and irradiated right lungs using the modified Ashcroft fibrosis scoring system. Hemi-thoracic irradiation increased fibrosis grade in a dose-dependent manner. Data are expressed as the mean ± SD (n = 2).