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. 2016 Jun 21;57(3):201–209. doi: 10.1093/jrr/rrv088

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© The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 5. — Thoracic computed tomography (CT) of non-irradiated or irradiated lungs in control, 25 Gy, and 30 Gy groups at 22 weeks post irradiation (IR). (A) Quantitative data obtained from thoracic CT scans regarding HU value (left), lung area ratio (middle) and cardiac right lateral shift (right). Hemi-thoracic irradiation to the lungs induced dose-dependent changes in three quantitative CT parameters. Data are expressed as the mean ± SD (n = 2). (B) Correlation analysis of quantitative CT parameters to histological fibrosis score. Three quantified CT parameters (HU value, lung area and cardiac right lateral shift) were strongly and significantly correlated to modified Ashcroft fibrosis scores (the Spearman's correlation coefficients were 0.886 [95% CI: 0.264–0.987], 0.886 [95% CI: 0.264–0.987] and 0.943 [95% CI: 0.559–0.994], respectively) (n = 6).