Table 3.

Upregulated genes in each group compared with the control group

Irradiation	Gene symbol	Gene description	Biological process
LDR 5 Gy	ZNF845	zinc finger protein 845	regulation of transcription
HDR 5 Gy	CRYAB	crystallin, alpha B	apoptotic process involved in morphogenesis
	IL18	interleukin 18	immune response
	SNORD113–4	small nucleolar RNA, C/D box 113–4	no data
	ZNF845	zinc finger protein 845	regulation of transcription
	SCARNA9	small Cajal body-specific RNA 9	no data
LDR 10 Gy	SNORD113–4	small nucleolar RNA, C/D box 113–4	no data
	IL18	interleukin 18	immune response
	CRYAB	crystallin, alpha B	apoptotic process involved in morphogenesis
	AREG	amphiregulin	G protein-coupled receptor signaling pathway
	ZNF845	zinc finger protein 845	regulation of transcription
HDR 10 Gy	IL18	interleukin 18	immune response
	SNORD113–4	small nucleolar RNA, C/D box 113–4	no data
	PRAME	preferentially expressed antigen in melanoma	positive regulation of cell proliferation
	ZNF845	zinc finger protein 845	regulation of transcription

LDR 5 Gy = cells irradiated with 5 Gy at the low-dose rate, HDR 5 Gy = cells irradiated with 5 Gy at the high-dose rate, LDR 10 Gy = cells irradiated with 10 Gy at the low-dose rate, HDR 10 Gy = cells irradiated with 10 Gy at the high-dose rate.