Table 4.

The list of up- and downregulated genes in the HDR 5 Gy group compared with the LDR 5 Gy group

Gene expression	Gene symbol	Gene description	Biological process
Upregulated in HDR 5 Gy	XAGE1D	cancer/testis antigen	no data
	NID2	nidogen 2	extracellular matrix organization
	LOX	lysyl oxidase	extracellular matrix organization
	MAMDC2	MAM domain-containing 2	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
	LOC100288114	hypothetical LOC100288114	no data
Downregulated in HDR 5 Gy	BMP5	bone morphogenetic protein 5	negative regulation of cell proliferation

LDR 5 Gy = cells irradiated with 5 Gy at the low-dose rate, HDR 5 Gy = cells irradiated with 5 Gy at the high-dose rate.