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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Environ Res. 2015 Nov 21;144(Pt A):139–148. doi: 10.1016/j.envres.2015.11.014

Fig. 1.

Fig. 1

Changes in DNAm related to prenatal cigarette smoke in childhood compared to at birth. (A) Differences in median DNAm levels (β) among SEED children, aged 3–5 years, with differing prenatal exposure to cigarette smoke. Single and double asterisks in the top panel denote CpG sites that reach statistical significance after correcting for multiple comparisons for active T2 and sustained maternal smoking, respectively. (B) Previously reported (Joubert et al., 2012) differences in median methylation levels (β) from Norwegian Mother and Child Cohort (MoBa) and Newborn Epigenetics Study (NEST) newborns associated with prenatal smoking exposure during T2.