Table 1. Clinical characteristics of diabetic (DB) or normoglycemic (NG) women with obesity from the ABOS cohort at inclusion (M0) and 12 months after surgery (M12).
| M0 | M12 | |||
|---|---|---|---|---|
| DB (n = 47) | NG (n = 44) | DB (n = 47) | NG (n = 44) | |
| Age, years | 47.2 ± 5.8 | 44.9 ± 7.1 | 48.2 ± 5.8 | 45.9 ± 7.1 |
| Weight, kg | 125.3 ± 18.4 | 126.3 ± 20.2 | 91.3 ± 17.2 | 94±18.0 |
| Weight loss, % | NA | NA | 26.9 ± 11.4 † | 25.0 ± 12.4 † |
| BMI, kg/m2 | 47 ± 6.1 | 45.5 ± 6.4 | 34.2 ± 5.9 † | 34.0 ± 6.7 † |
| usCRP, mg/L | 7.2 ± 3.1 | 6.9 ± 3.3 | 2.6 ± 2.8 † | 3.3 ± 3.3 † |
| HbA1c, % | 7.2 ± 1.4 | 5.8 ± 0.3* | 5.9 ± 0.7 † | 5.6 ± 0.3* † |
| Fasting glucose, mmol/L | 8.1 ± 2.9 | 5.4 ± 0.4* | 5.6 ± 1.7 † | 4.9 ± 0.5* † |
| 2H glucose, mmol/L | 12.6 ± 4.6 | 6.0 ± 1.2* | 5.8 ± 3.6 † | 5.2 ± 1.8 † |
| Fasting insulin, pmol/L | 100.1 ± 58.9 | 81.2 ± 36.4 | 56.2 ± 81.0 † | 41.1 ± 25.0 † |
| HOMA2-S, % | 84.0 ± 149.1 | 79.7 ± 37.8 | 176.4 ± 118.6 † | 179.2 ± 104.7 † |
| HOMA2-B, % | 69.0 ± 44.8 | 108.2 ± 34.0* | 70.1 ± 28.5 | 78.5 ± 26.3 † |
| HOMA2-BS, % | 38.6 ± 23.0 | 76.5 ± 19.0* | 104.9 ± 53.8 † | 121.6 ± 44.8 † |
| Surgery (AGB/RYGB) | 7/40 | 15/29 | 7/40 | 15/29 |
| Remission (Yes/No) | NA | NA | 29/18 | NA |
Data are presented as mean ± SD,
* p < 0.05 t-test was used for statistical analyses between diabetic and normoglycemic women at M0 and M12.
† p < 0.05 paired t-test was used for statistical analyses between baseline and at 12 months after surgery.
usCRP, ultrasensitive C Reactive Protein;
AGB, adjustable gastric banding;
RYGB, Roux-y-Gastric Bypass