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. 2016 Jun 21;11(6):e0157303. doi: 10.1371/journal.pone.0157303

Table 7. The areas under the ROC curve (AUC), sensitivity and specificity by the optimized cut-off points for metabolic risk factors associated with the presence of albuminuria (> 30mg/day).

Risk factor AUC (95% CI) Cut-off according to Youden's index Sensitivity (%) Specificity (%)
Male (n = 10,343)
WC (cm) 0.643 (0.622–0.664) 90.8 54.2 68.8
WHtR 0.644 (0.623–0.665) 0.53 61.6 61.6
MAP (mmHg) 0.695 (0.675–0.715) 97.9 56.7 72.5
FPG (mmole/L) 0.674 (0.654–0.695) 5.40 54.8 70.0
TG/HDL-C ratio 0.614 (0.593–0.635) 1.13 67.3 49.0
Female (n = 8,091)
WC (cm) 0.646 (0.613–0.680) 80.75 56.7 68.0
WHtR 0.649 (0.615–0.682) 0.52 56.4 70.4
MAP (mmHg) 0.706 (0.676–0.737) 91.9 55.6 76.9
FPG (mmole/L) 0.622 (0.589–0.656) 5.28 51.5 68.8
TG/HDL-C ratio 0.629 (0.597–0.660) 1.08 40.4 80.9

WC, waist circumference; WHtR, waist-to-height ratio; MAP, mean arterial pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; TG, total cholesterol.