Table 3. Factors associated with abnormally reduced pRNFL thickness.

Parameter	Univariate OR (95% CI)	P value	Multivariate OR (95% CI)	P value
Age	1.009 (0.970–1.050)	0.663
Onset age	0.983 (0.893–1.082)	0.731
LFS	0.836 (0.552–1.267)	0.399
WBC	0.999 (0.998–1.000)	0.124
Lymphocyte	0.999 (0.999–1.000)	0.108
ESR	1.013 (0.995–1.032)	0.149
CRP	1.014 (0.683–1.507)	0.944
IgG	1.001 (1.000–1.002)	0.057	1.001 (1.000–1.002)	0.203
IgM	0.993 (0.984–1.002)	0.125
IgA	1.004 (1.000–1.007)	0.083	1.003 (0.998–1.007)	0.228
ANA positivity	0.396 (0.034–4.572)	0.458
Anti–SSA positivity	2.874 (0.356–23.190)	0.322
Anti–SSB positivity	3.977 (1.522–10.391)	0.005	3.155 (1.009–9.870)	0.048
RF positivity	1.535 (0.607–3.881)	0.365

pRNFL, peripapillary retinal nerve fiber layer; OR, odd ratio; CI, confidence interval; LFS, lymphocytic focus score; WBC, white blood cell; Ig, Immunoglobulin; RF, rheumatoid factor; ANA, antinuclear antibody; Anti–SSA/SSB, anti–Sjögren’s syndrome A and/or B antibodies; ESR, erythrocyte sedimentation rate; CRP, C–reactive protein.

Statistically significant values are in bold.