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. 2016 Jun 21;11(6):e0157995. doi: 10.1371/journal.pone.0157995

Table 4. Factors associated with abnormally reduced mGCIPL thickness.

Parameter Univariate OR (95% CI) P value Multivariate OR (95% CI) P value
Age 1.013 (0.979–1.048) 0.462
Onset age 1.026 (0.947–1.112) 0.528
LFS 1.075 (0.774–1.491) 0.667
WBC 1.000 (0.999–1.000) 0.367
Lymphocyte 1.000 (0.999–1.000) 0.398
ESR 1.026 (1.009–1.044) 0.003 1.026 (1.002–1.051) 0.031
CRP 1.030 (0.738–1.440) 0.860
IgG 1.001 (1.000–1.001) 0.160
IgM 1.001 (0.997–1.004) 0.737
IgA 1.003 (1.000–1.007) 0.080 1.001 (0.996–1.005) 0.764
ANA positivity 0.674 (0.059–7.680) 0.750
Anti–SSA positivity 2.188 (0.463–10.335) 0.323
Anti–SSB positivity 4.779 (2.064–11.065) <0.001 4.175 (1.557–11.195) 0.005
RF positivity 1.151 (0.511–2.593) 0.734

mGCIPL, macular ganglion cell–inner plexiform layer pRNFL, peripapillary retinal nerve fiber layer; OR, odd ratio; CI, confidence interval; LFS, lymphocytic focus score; WBC, white blood cell; Ig, Immunoglobulin; RF, rheumatoid factor; ANA, antinuclear antibody; Anti–SSA/SSB, anti–Sjögren’s syndrome A and/or B antibodies; ESR, erythrocyte sedimentation rate; CRP, C–reactive protein.

Statistically significant values are in bold.