Table 4. Kinetic constants for trelagliptin determined from association progress curves.
| parameter | Ki*(nmol/L) | kon (M-1 sec-1) | koff (sec-1) | EI* t1/2 (min) |
|---|---|---|---|---|
| trelagliptin | 1.5 ± 0.1 | (2.6 ± 0.1) x 105 | (4.0 ± 0.5) x 10−4 | 29 |
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