Table 1. characteristics of the population without pulmonary rehabilitation (usual cares) and with pulmonary rehabilitation (PR); ⁺% non smokers/ex-smokers/smokers; ⁺⁺% of patients at least 1 exacerbation per year.

	Usual Cares	PR	Ref
Distribution according to severity (%patients)			[24]
GOLD2	88.3	88.3
GOLD3	10.5	10.5
GOLD4	1.2	1.2
Smoking initial status+			[24]
GOLD2	12.5/62.2 /25.3	12.5/62.2 /25.3
GOLD3	10.2/63.6/26.3	10.2/63.6/26.3
GOLD4	8.7/71.4/19.9	8.7/71.4/19.9
Smoking status turnover (% patients each)			[30]
smoking cessation (% smokers)	4.7	4.7
smoking relapse (% ex-smokers)	2.6	2.6
Age distribution according to severity	Table S1	Table S1	[22]
Transition probability from one stage to another	Table S2	Table S2	[22]
Probability of death according to COPD stage	Table S3	Table S3	[22]
Rate of exacerbations++			[28]
GOLD2	39.45	39.45
GOLD3	44.1	44.1
GOLD4	66.7	66.7
Heath utilities (0 / at least 1 exacerbation)			[27]
GOLD2	0.755; 0.736	0.755; 0.736
GOLD3	0.748; 0.726	0.748; 0.726
GOLD4	0.549; 0.535	0.549; 0.535
Additional utility due to rehabilitation		0.09
Heath costs (€ per patient and per year)			[25]
GOLD2	5398	5398
GOLD3	5567	5567
GOLD4	10953	10953
Additional cost for PR (€ per patient per year)		1583	[26]