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. 2016 Jun 21;11(6):e0157738. doi: 10.1371/journal.pone.0157738

Table 1. Demographic characteristics, ischemic lesion size on initial and follow-up DWI, as well as perfusion deficit size on initial PWI in patients with and without HARM.

median (IQR), HARM, No HARM OR; 95%CI p
unless noted n = 8 n = 8
Age, years 67.5 (63.75–73) 73 (41–83.5) 0.72
Male sex (n, %) 5 (62.5%) 4 (50%) 1.67; 0.23–12.22 0.61
CKD 1 (12.5%) 1 (12.5%) 1.00; 0.05–19.36 1.00
Time between onset 104 (85–117) 336 (77–360) 0.46
and MRI, minutes
Time between 10.5 (5.25–17.75) 19.5 (15.5–23.5) 0.03
MRI 1/2, hours
MRI 1
DWI lesion size, cm3 3.55 (0.55–4.28) 2.05 (0.75–10.45) 0.72
PWI lesion size, cm3 30.85 (13.5–41.25) 30.9 (25–37.5) 0.72
rCBF 0.65 (0.58–0.97) 0.85 (0.57–0.97) 0.63
rCBV 0.89 (0.67–1.05) 1.02 (0.70–1.17) 0.37
MRI 2
DWI lesion size, cm3 3.3 (1.03–8.23) 16.35 (4.4–35.18) 0.05
Recanalization 7 (87.5%) 3 (37.5%) 11.67; 0.92–147.56 0.04
Infarction growth, cm3 0.15 (-0.15–3.55) 7.6 (3.35–31.35) 0.01

Legend: HARM = hyperintense acute reperfusion marker, CKD = chronic kidney disease, DWI = diffusion-weighted imaging, PWI = perfusion-weighted imaging