Table 2.
IC50 of MDA and EPI-R cells to EPI, taxol, etoposide, and cisplatin
| Agents | IC50 (48 hrs) |
RI48 | IC50 (72 hrs) |
RI72 | ||
|---|---|---|---|---|---|---|
| MDA | EPI-R | MDA | EPI-R | |||
| EPI | 1.65±0.18 | 23.55±0.75* | 14.27 | 0.22±0.05 | 11.88±0.14* | 54.98 |
| taxol | 3.66±0.44 | 21.65±0.52* | 5.92 | 0.79±0.13 | 9.674±0.1* | 12.26 |
| etoposide | 8.3±0.24 | 10.5±0.33* | 1.27 | 2.97±0.07 | 5.173±0.04* | 1.74 |
| cisplatin | 4.97±0.14 | 8.52±0.19* | 1.71 | 1.31±0.01 | 7.034±0.06* | 5.36 |
IC50 was measured in cells incubated with each of these drugs for 48 and 72 hrs. T-test, n = 3 in each group,
p < 0.05