Table 1.
Neutraling titers, IC50 | |||||
---|---|---|---|---|---|
Group | Dose | Animal | Day0 | Day3 | Day6/7 |
IVAG | 10mg/kg | 11-001 | 2372 | 1939 | 1000 |
11-007 | 1977 | 1477 | 751 | ||
11-009 | 2447 | 1484 | 823 | ||
11-015 | 1912 | 658 | 923 | ||
11-017 | 1378 | 457 | 127 | ||
2mg/kg | 11-059 | 109 | 56 | <50 | |
11-063 | 174 | 110 | 70 | ||
11-065 | 293 | 217 | 79 | ||
11-067 | 254 | 219 | 93 | ||
11-069 | 427 | 279 | 169 | ||
0.4mg/kg | 11-071 | 50 | <50 | <50 | |
11-073 | 51 | <50 | <50 | ||
11-075 | 75 | <50 | <50 | ||
11-077 | <50 | <50 | <50 | ||
11-079 | 46 | <50 | <50 | ||
IR | 10mg/kg | RAs14 | 2354 | 1333 | 954 |
RMm14 | 2838 | 1333 | 968 | ||
REn14 | 1839 | 1387 | 928 | ||
RPr14 | 2761 | 1731 | 450 | ||
2mg/kg | ROt14 | 328 | 181 | 123 | |
RFr14 | 798 | 443 | 257 | ||
RNg14 | 462 | 289 | 153 | ||
RQg14 | 451 | 233 | 180 | ||
0.4mg/kg | RAo14 | 52 | <50 | <50 | |
RYt14 | 71 | <50 | <50 | ||
RQr14 | 96 | 52 | <50 | ||
RPn14 | <50 | <50 | <50 |
Numbers represent reciprocal dilution of serum producing 50% neutralization.
Days after antibody administration, day 0 is the day of challenge.