Figure 5.
Reconstitution of the biosynthesis of 1 in Aspergillus nidulans A1145 and loss of stereoselective product formation upon elimination of cghA. HPLC traces of metabolic extracts from the culture of (i) wild-type A. nidulans A1145 control, (ii) A. nidulans harboring cghA, cghB, cghC and cghG and (iii) A. nidulans harboring cghB, cghC and cghG. Authentic reference of (iv) 1 and (v) 7.