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. Author manuscript; available in PMC: 2017 Jun 21.
Published in final edited form as: Anal Chem. 2016 May 27;88(12):6547–6553. doi: 10.1021/acs.analchem.6b01344

Figure 2.

Figure 2

TERS imaging of integrin α5β1 (a–c) and αvβ3 (d–f) immobilized on glass slides. The upper row are experiments for α5β1 and the lower row corresponds to αvβ3 receptors. (a, d) 3-D TERS mapping of generated from single peak intensity at (a) 1304 cm−1 and (d) 1452 cm−1. (b, e) 32×32 MCR score map generated from (b) LV(α5β1) and (e) LV(αvβ3). (c, f) Enhanced TERS spectra of (c) α5β1 and (f) αvβ3 extracted from the high intensity pixels (rectangular boxes) in (b) and (e). Scan area: 2×2 μm2. Step size: 62.5 nm per pixel.